Panthers’ Week 2 outlook tightens as injuries hit the trenches. Wharton’s hamstring will sideline him 2-4 weeks, testing interior depth while Nijman’s Week 1 effort underscored protection issues. Renfrow’s rib injury adds another cut to the receiving corps, with Jones II limited and Crumedy/Jaden Crumedy stepping into larger roles. Cam Jackson could push for more snaps behind Wharton, reshaping the Panthers’ front seven against Arizona.

Fantasy angles shift quickly: Renfrow’s status could boost other receivers in a game Carolina leans on quick throws and run game tempo. With the rookie interior guys stepping up, IDP edges may see increased opportunity, and Young’s sophomore season starts under new pressure, raising the stakes for Week 2 projections and DFS lineups.

The Giants open Week 1 in Washington armed with six victory pillars: minimize unforced errors, establish the run, attack Washington’s right-side O-line, unleash Russell Wilson on deep balls, tackle with discipline, and control the clock to shield the offense from penalties and turnovers. The plan hinges on Tyrone Tracy Jr. pounding the ground game while Wilson leverages play-action and big-play potential to boost the Giants’ fantasy upside in a hostile environment.

Moonball Russ aims to unlock explosiveness with Malik Nabers’ speed, while the club’s ball-security emphasis keeps Washington’s opportunistic defense from tipping the balance. In short, a balanced, mistake-free attack paired with stout tackling and clock management should tilt a Week 1 slugfest in New York’s favor, giving fantasy managers a few cornerstone weeks to ride the momentum.

Week 2 of the 2025 NFL preseason highlights fresh fantasy angles: Cam Ward noticias in Tennessee as he builds rapport with Calvin Ridley, with raft-ready rookies like Jalen Royals and Rashee Rice testing speed and playmaking in Reid’s system. Tory Horton and Jaxon Smith-Njigba push Seattle’s WR room, while Tetairoa McMillan nudges Cam Newton’s Panthers roster moves with big-play potential. The Cowboys’ Jaydon Blue returns to action, Cowboys’ backfield competition heats up, and Shedeur Sanders earns more reps for Cleveland as the QB depth chart shakes out.

Further chess moves come from Mounting QB battles to watch: Hendon Hooker lighting up Lions camp chatter, Trevor Lawrence anchoring Jacksonville’s offense, and Aaron Rodgers nudging Pittsburgh’s offense into sharper focus in preseason. This slate is ripe for late-draft steals and depth-spark players who could push into fantasy rosters by Week 1 if opportunities open up late in August.